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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MYBL2 All Species: 26.97
Human Site: S435 Identified Species: 45.64
UniProt: P10244 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P10244 NP_002457.1 700 78764 S435 T S L S F L D S C N S L T P K
Chimpanzee Pan troglodytes XP_514658 769 86303 S435 T S L S F L D S C N S L T P K
Rhesus Macaque Macaca mulatta XP_001084853 700 78675 S435 T S L S F L D S C N S L T P K
Dog Lupus familis XP_534424 883 97262 S618 A S L S F L D S C N S L T P K
Cat Felis silvestris
Mouse Mus musculus P48972 704 79084 S438 A S L S F L D S C N S L T P K
Rat Rattus norvegicus NP_001100006 704 79549 S439 A S L S F L D S C N S L T P K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511778 753 85883 D471 H N D G S L N D A I G I T L K
Chicken Gallus gallus Q03237 686 77718 S418 T S L S F L D S C N S M T P K
Frog Xenopus laevis P52551 743 82891 C438 S L T S T P V C S Q K T M V T
Zebra Danio Brachydanio rerio NP_001003867 633 70853 Q392 F L N M W T K Q D T L D L E N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797351 686 76826 C441 N G S T S A T C S S S L L L T
Poplar Tree Populus trichocarpa
Maize Zea mays P20024 340 36221 P99 S K I A A C L P G R T D N E I
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9S7G7 776 86488 Y507 N D G F I D T Y G H V T S H G
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa O13493 324 36522 W83 V D L K G P R W A D I A R K L
Conservation
Percent
Protein Identity: 100 88 98.2 72.5 N.A. 85.2 87.7 N.A. 38.3 72.5 54.2 52.1 N.A. N.A. N.A. N.A. 37.8
Protein Similarity: 100 89.7 98.7 74.7 N.A. 89.4 91.3 N.A. 54.5 81.5 69 65.8 N.A. N.A. N.A. N.A. 54
P-Site Identity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. 20 93.3 6.6 0 N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. 40 100 13.3 6.6 N.A. N.A. N.A. N.A. 26.6
Percent
Protein Identity: N.A. 20.1 N.A. 25.5 N.A. 20.7
Protein Similarity: N.A. 31.8 N.A. 40.8 N.A. 29.5
P-Site Identity: N.A. 0 N.A. 0 N.A. 6.6
P-Site Similarity: N.A. 26.6 N.A. 13.3 N.A. 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 22 0 0 8 8 8 0 0 15 0 0 8 0 0 0 % A
% Cys: 0 0 0 0 0 8 0 15 50 0 0 0 0 0 0 % C
% Asp: 0 15 8 0 0 8 50 8 8 8 0 15 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 15 0 % E
% Phe: 8 0 0 8 50 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 8 8 8 8 0 0 0 15 0 8 0 0 0 8 % G
% His: 8 0 0 0 0 0 0 0 0 8 0 0 0 8 0 % H
% Ile: 0 0 8 0 8 0 0 0 0 8 8 8 0 0 8 % I
% Lys: 0 8 0 8 0 0 8 0 0 0 8 0 0 8 58 % K
% Leu: 0 15 58 0 0 58 8 0 0 0 8 50 15 15 8 % L
% Met: 0 0 0 8 0 0 0 0 0 0 0 8 8 0 0 % M
% Asn: 15 8 8 0 0 0 8 0 0 50 0 0 8 0 8 % N
% Pro: 0 0 0 0 0 15 0 8 0 0 0 0 0 50 0 % P
% Gln: 0 0 0 0 0 0 0 8 0 8 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 8 0 0 8 0 0 8 0 0 % R
% Ser: 15 50 8 58 15 0 0 50 15 8 58 0 8 0 0 % S
% Thr: 29 0 8 8 8 8 15 0 0 8 8 15 58 0 15 % T
% Val: 8 0 0 0 0 0 8 0 0 0 8 0 0 8 0 % V
% Trp: 0 0 0 0 8 0 0 8 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _